Lipid nanocarrier-based drug delivery systems: therapeutic advances in the treatment of lung cancer
Diabetes (2016) 65:1196207
The full notice is available at federalregister.gov
Use of the enzyme component system according to claims 1 to 45 in a process for enzymatic coal liquefaction, wherein the reaction of the enzyme component system takes place in a pH range of pH 2 to 11, preferably pH 3 to 9, at a temperature from 20 to 95 C, preferably 40 to 95 C, at a consistency of 0.5 to 40%, preferably at a consistency of 4 to 15%, in the presence of oxygen or air at normal pressure to slight O 2 excess pressure (up to 2 bar) is carried out and the system component 1: lipase from Humicola lanuginosa in a concentration of 00.5 to 20 mg, preferably from 0.05 to 10 mg and the system component 2: fatty acids in one or more forms, preferably C 8 to C 6 , preferably tetradecanoic acid and / or dodecanoic acid in a concentration of 0.05 to 100 mg, preferably in a concentration of 0.05 to 50 mg and the system component 3: precursor oxidizing agent, preferably HO 2 in a concentration of 0.05 to 100 mg (100%), preferably in a concentration from 0.05 to 50 mg and the system component 4: ketones, preferably benzophenones in a concentration of 0.05 to 100 mg, preferably in a concentration of 0.05 to 50 mg, based on 1g of coal (lignite)
