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However, after irradiation, GPx1-KO and wild-type mice exhibited almost similar levels of intestinal GPx activity, and this was due to the radiation-induced compensatory upregulation of GPx2 in GPx1-KO mice

Considering the anti-inflammatory and antioxidant properties of Se, it can be considered an attractive therapeutic strategy in relieving inflammation-related conditions in critically ill patients

Wagner, et al

In many cases, you might not even experience any symptoms or they might be really mild, making it hard for you to notice them as something out of the ordinary