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This implies that boehmite nanozymes can be used for treating Huntington disease (HD) (Martnez-Camarena et al., 2022)

One possible explanation for such a response is that inhibition of mTORC1 and activation of GCN2 collectively suppresses global translation to conserve nutrients, while selective translation of mRNA such as ATF4 (mediated by increased p-eIF2) activates the expression of AARE genes to mitigate cellular stress