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Nanoparticle-based codelivery strategies achieve spatiotemporal synergy between ferroptosis inducers and immunomodulators through precise drug release control, potentially overcoming BBB limitations and reducing systemic toxicity, thereby improving clinical translation feasibility

In turn, numerous types of cells (including endothelial cells and hepatocytes), are able to take up albumin by receptor-mediated endocytosis and break it down by lysosomes (8,32)