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Network centrality analysis of the Angptl signaling identified that alveolar and transient macrophages are the most prominent sources and dominant mediators for this ligand and has a predominant paracrine effect on other endothelial cells ( Figure 10B )

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The germinal center B-cell-like (GCB) subtype of diffuse large B-cell lymphoma (DLBCL) is highly sensitive to the ferroptosis inducer dimethyl fumarate (DMF) due to low GPX4 expression and high 5-LOX expression (163)

Patients typically present with nephritic syndrome, characterized by acute renal failure, hypertension, hematuria, and red blood cell casts