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Studies show that approximately 1% of a high-dose B12 supplement is absorbed through passive diffusion along the entire gastrointestinal tract, completely bypassing the need for Intrinsic Factor or perfect stomach acid levels

G., Nagababu, E., & Rifkind, J

Acknowledgements The authors would like to thank Claire Powers at the Viral Vector Core Facility, University of Oxford, for assistance in generating and supplying the rMVA-EE2-MCP construct