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4C), these results demonstrate that system x c - activity promotes glucose deprivation-induced cell death through import of L-cystine, depletion of GSH and consumption of NADPH by L-cystine reduction to L-cysteine

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Cell adhesion, invasion, and cell cycle The conditions required for the development of endometriosis include the detachment of endometrial epithelial cells from their primary site, the adhesion of endometrial cells outside the uterine cavity in a host tissue, their invasion, and their proliferation

Cytochrome c release assay Cells were fractionated to obtain cytoplasmic and mitochondria-enriched fractions using Dounce homogenization and differential centrifugation as per the Abcam cytochrome c release kit (ab65311)