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When collected and analyzed using rigorous methodological standards, RWE can provide insights into care patterns, treatment performance, and patient outcomes that may not be captured by RCTs alone, supporting both clinical and policy decision-making

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If the GP says that she doesn't have macrocytic anaemia so doesn't need this pattern of treatment, you could point out that NICE guidelines for B12 deficiency say that "Note: clinical features of vitamin B12 deficiency can occur without anaemia and without low serum levels of vitamin B12." cks.nice.org.uk/topics/anae

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