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This material may be used in non-clinical research involving peptide identification, molecular characterization, stability assessment, purity analysis, and other controlled analytical procedures

BTBR mice showed suppressed hippocampal neurogenesis, but curcumin restored progenitor proliferation and enhanced neural differentiation, suggesting that early curcumin exposure exerts long-lasting benefits (Zhong et al., 2020)

Furthermore, loss of immunoreactivity to APE1 was observed in spinal cords of pre-symptomatic SOD1 G93A mice, suggesting that reduced levels of APE1 in motor neurons precede neurodegeneration (Manabe et al., 2001

This would call for the development of robust, consistent protocols for the identification and attribution of costs to particular programmes