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SGK1 inhibition in glia ameliorates pathologies and symptoms in Parkinson disease animal models

Born and raised in the Netherlands, Blank fell in love with classic American cinema

Schweizer et al (62) demonstrated that the pharmacological application of chaetocin confers neuroprotection in cellular models of cerebral ischemia, concomitant with enhanced histone H3K9 acetylation at BDNF promoter regions, which mechanistically underlies the upregulation of neurotrophin transcription