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found no improvements in bone strength or microarchitecture with liraglutide, suggesting that the effects of GLP-1 receptor agonists on bone remodeling may be context-dependent and influenced by metabolic conditions

Breen EC, Reynolds SM, Cox C, Jacobson LP, Magpantay L, Mulder CB, et al

GLP-1 ( , :2 (MEDI7219)) .As provided herein, GLP-1 peptide analogs administered in the oral formulations provided herein (eg, SEQ ID NO:2 or ammonium acetate salt thereof (MEDI7219)) can be absorbed in the proximal colon