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ROS also attack unsaturated fatty acids in cell membranes and lipoproteins, triggering lipid peroxidation that compromises membrane integrity and fluidity [109]

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It is known to provide a physiologically acceptable electrical current(0.1-1.0 mA/cm 2 ) using an electrode of the same polarity to drive charged permeants across the SC through its potential gradient [249, 250]

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