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After treatment, samples were alkylated either by Procedure A with IAM-TPP (1 mM) or by Procedure B with IAM (1 mM) for 30 min at RT in the dark

(PubMed) Boehnke C, Reuter U, Flach U, Schuh-Hofer S, Einhaupl KM, Arnold G

Molecular docking experiments have demonstrated that nicotinic acid interacts with TLR4, inhibiting the assembly of the NLRP3-ASC-Caspase-1 complex, suppressing pyroptosis, and alleviating NASH [164]

According to epidemiological analysis, acne currently affects up to 20.5% of the global population, with its incidence rates continuing to increase rapidly [4, 5]