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[16] Melanotan-II may cause reversible darkening of moles and freckles

It was also associated with an increased lifespan." "Being sexually intact or having an OSS [ovary-sparing spay] were associated with lower odds of orthopedic problems, consistent with other studies showing lower risks of a variety of orthopedic problems in sexually intact dogs as compared to gonadectomized dogs." "Our results were also consistent with previous studies indicating that the associated odds of cancer is significantly lower for sexually intact dogs than gonadectomized dogs

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