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Since specific mediators driving changes in dysfunctional CD8 + T cell subsets in cirrhosis need further investigation, and their clinical relevance is yet to be fully understood, current immunotherapy strategies for cirrhosis predominantly target cells other than CD8 + T cells, such as macrophages

10.1007/s12274-021-3432-x [DOI] [Google Scholar] Zhao Z., Song X., Zhang Y., Zeng B., Wu H., Guo S

1-1.5 mg of nuclear lysates were diluted in IP buffer, pre-cleared with 15 l A/G plus agarose beads (Santa Cruz) and incubated for 5 hours with 20 l of GFP-Trap beads (Proteintech)

Li YC, Wang FM, Pan Y, Qiang LQ, Cheng G, Zhang WY, et al