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Comp Biochem Physiol Part C: Toxicol Pharmacol (2009) 150(1):7984

Muscle contractions from mechanical loading induce microtrauma in muscle fibers, resulting in the rupture of the extracellular matrix, basal lamina, and sarcolemma, in addition to the alteration of calcium homeostasis, which promotes changes in the cell membrane structure and permeability [48, 49]