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Chandyo RK, Kvestad I, Ulak M, et al.

With the increasing presence of so-called contaminants of emerging concern (CECs), such as pharmaceutical residues and industrial chemicals in source waters (Zhang et al

Extracellular NAD + independent of ATP and cGAMP ( Figure 1 + to ADPR, AMP, and ADO, respectively, bypassing ATP- and cGAMP-dependent routes ( + -dependent pathway is highly active in the hypoxic and acidic BM niche, favoring ADO accumulation