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All these condition prevents the absorption of crucial nutrients, including vitamin B6, from the digestive tract

While there is not much doubt that traumatic disc herniation can occur in a degenerated segment, 5 and, although documented in biomechanical in-vitro studies, 39 the existence of an isolated annulus fiber rupture with NP herniation caused by a single traumatic event without (proven) pre-existing DD is still debated in the clinical literature

These studies support the existence of rare, highly penetrant PGVs that contribute to a subset of LCINS

instead, they follow a precisely timed and organized cascade that corresponds with the development of distinct cell types in the wound at various stages of the healing process