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PBGD, porphobilinogen deaminase

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Look for active ingredients like salicylic acid (BHA) or benzoyl peroxide, she says, recommending a gel-based wash to minimize heavy occlusion. To avoid irritation, she advises keeping exfoliation to two to three times per week if using acids, and cautions to avoid heavy, highly fragranced washes. For eczema-prone or sensitive skin, she emphasizes restraint above all else, advising people to prioritize fragrance-free and dye-free formulas, seek out colloidal oatmeal, ceramides, and mild surfactants, and avoid exfoliating acids unless specifically advised by a dermatologist. She adds that short ingredient lists reduce the chance of irritation, making them especially important for compromised or reactive skin

Interestingly, the breakdown of mitochondrial respiratory, resulting in the reduction of ROS formation has been shown to suppress tumorigenesis (Weinberg et al 2010)