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Optimization of oxidative stress for mesenchymal stromal/stem cell engraftment, function and longevity

Serine is the major substrate driving folate cycle flux for the generation of cytoplasmic NADPH by the enzyme ALDH1L1 ( + ] is through increasing the rate of glutaminolysis (Figure 2E)

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318 Spinal cord injuries can interrupt ascending and descending pathways, resulting in loss of sensation or motor function below the level of the lesion