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Description

(2) targeting System Xc (inhibit System Xc activity and prevent GSH synthesis)

Fungal peroxisomes are specialized in both anabolism and catabolism with very important functions for cell protection by detoxifying and sequestering reactive oxygen species 49,50

Whole genome sequencing, assembly, and annotation A total of 72 Nanopelagicales strains were isolated and grown in 400500 ml culture medium until stationary phase

Genes associated with resistance include those conferring target-site resistance (e.g., mutations in the voltage-sensitive sodium channel ( VSSC ) gene, also known as kdr mutations 3 ) or metabolic resistance (e.g., glutathione S-transferase ( GST ) 1 and cytochrome P450 ( P450 or CYP ) genes 4 )