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It also plays a role in maintaining healthy liver and brain function

Jaundice Jaundice (or icterus) is a physical sign characterized by a yellow appearance of the skin, mucous membranes, and sclera caused by bilirubin deposition

[DOI] [PubMed] [Google Scholar] 58.Yin Z., Ivanov V.N., Habelhah H., Tew K., Ronai Z

In some embodiments, the assay is a cell-based assay, e.g., one comprising the steps of: contacting (a) a cell of interest (e.g., a monocyte and/or macrophage) with a test agent, and determining the ability of the test agent to modulate (e.g., up-regulate or down-regulate) the copy number, amount, and/or activity (e.g., binding between one or more biomarkers and one or more natural binding partners) of one or more biomarkers