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DOI:10.1038/nn1609 [ Links ] 6

Microglia are initially activated to stage 1 DAM, which are characterized by a downregulation of homeostatic microglial genes including p2ry12 and cx3cr1 , and an upregulation of genes including trem2 , tyrobp and apoe

To assess whether Gclc interferes with the development of MZB, which generally populate the spleen 23 weeks after birth 59 , we investigated the distribution of discrete maturation steps in the spleen