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The initial interest in T4 and its analog TB500 stems from their roles in: Accelerating wound healing Promoting blood vessel formation (angiogenesis) Reducing inflammation Supporting tissue regeneration Thymosin beta4 promotes cell migration and differentiation and has been shown to facilitate tissue regeneration in multiple organ systems. Malinda et al., Annals of the New York Academy of Sciences TB500 vs

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After confirming the accurate delivery of BMAC to the site of bone marrow injury using a Grams needle and C-arm fluoroscopy, the BMAC was injected into the subchondral bone at the lesion site using an osteotomy needle