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C/EBP-null (knockout) mice lack functionally mature granulocytes

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Most studies report: No observable toxicity No organ damage No carcinogenic findings in short-term studies However: Long-term human clinical data is limited Most evidence remains preclinical Reference: Sikiric et al., 2018 safety review Summary: BPC-157 Peptide BPC 157 peptides are among the most studied regenerative peptides in experimental research