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(i) Toxic metals can be found in locus ceruleus neurons from the second decade of life onwards (43) and the locus ceruleus is the region of the brain first affected by AD, with tangle pathology detected in these neurons from before puberty or in early young adulthood (174)

A regression curve correlating CFU/mL with OD 600 was established using the drop plate technique 36 to determine bacterial cell number

However, the ntp 1 589708 strain exhibited a partially restored colony phenotype relative to the ntp1 strain (Fig

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