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However, observational studies are open to residual confounding, such as by socioeconomic position and health status, and cannot distinguish whether l-carnitine is a biomarker or a causal factor, making them difficult to use as a guide to interventions [17]

It is particularly important to note that an increasing number of studies have shown that in TC, there is a bidirectional relationship between DNA methylation and metabolic reprogramming

8 However, in the case of a hypertensive treatment in the presence of carnitine, a dramatic reduction of the eye to cup phenomenon is observed (Figure 3)