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Oxidative stress reactions, particularly the excessive generation of reactive oxygen species (ROS), may interfere with the function of the hypothalamic-pituitary-adrenal (HPA) axis, leading to hormonal imbalances that impact sleep and physical stamina (Spiers et al., 2015)

Such efforts will be instrumental in guiding evidence-based recommendations and optimizing the safe integration of curcumin into nephrological practice

this expression of klotho, proven by immunohistochemistry, was higher in non-GH-secreting adenomas, suggesting that non-GH-secreting pituitary cells are capable of producing klotho

Nat Biotechnol 40:815817 Kustatscher G, Collins T, Gingras AC, Guo T, Hermjakob H, Ideker T, Lilley KS, Lundberg E, Marcotte EM, Ralser M et al (2022b) Understudied proteins: opportunities and challenges for functional proteomics