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Hypoxia significantly limits the efficacy of RT by inducing radio-resistance and promoting tumor metastasis [237]

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Bang MH, Van Riep T, Thinh NT, Song le H, Dung TT, Van Truong L,

This topic certainly deserves further investigation in the future

Main body This review outlines current insights into the diseases pathophysiology and delves into the key mechanisms involved, including oxidative stress, lipid dysregulation, and insulin resistance