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[4] [6] The direct delivery of ascorbic acid into the bloodstream allows for supraphysiological concentrations, which could have distinct biological effects, such as pro-oxidant activity in the presence of transition metals or selective cytotoxicity against certain malignant cells, although these applications remain under investigation and are not universally accepted as standard of care

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This route of administration can be particularly beneficial for patients who have difficulty swallowing oral medications or for those where oral administration is not optimal due to gastrointestinal issues