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Review criteria Published research papers, clinical trials, and literature reviews were selected using different keywords (e.g., NF1, neurofibroma, malignant peripheral nerve sheath tumour, optic glioma) and database sources (e.g., PubMed, Google Scholar, ISI Proceedings, Journal storage [JSTOR] Search, Medline, Scopus, Web of Science, Clinicaltrials.gov)

doi: 10.1016/j.biomaterials.2024.122510

Once the tumour became arrested in the palbociclib-treated group, mice were further randomized to receive either RSL3 (50 mg kg 1 , two times per week for 2 weeks) or the vehicle, resulting in four experimental groups: vehicle, RSL3, palbociclib and palbociclib + RSL3