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The lack of difference in the growth of AgRP GHR KO mice, as compared to control mice, is interesting since previous studies suggested that NPY plays a role regulating GH secretion and consequently somatic growth 36,37,38

Astragaloside IV mitigates cerebral ischaemia-reperfusion injury via inhibition of P62/Keap1/Nrf2 pathway-mediated ferroptosis

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Clinical alterations resulting from these mutations are hypothesized to be derived from either loss or gain of function of GCase and interaction with its substrates like glycosphingolipids (GSLs), glucosylceramide (GlcCer) and glucosylsphingosine (GlcSph)