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In newborns, common early symptoms are poor feeding, vomiting, lethargy, hyperventilation resulting often in respiratory alkalosis, and irritability that rapidly progresses to seizures, deep coma, and even death if not urgently treated

A previous in vitro study demonstrated that 7-day exposure of motor neurons to fluvastatin has less effects on spinal motor neurons in a dose-dependent manner (Murinson et al., 2012)

Other modalities, such as acupuncture and moxibustion, are believed to improve organ function and overall regulation by modulating neuroimmune pathways and reducing inflammatory responses, although their specific impact on TMAO requires further investigation (Sun et al., 2024)

Moon YA, Horton JD