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Description

Nicotinamide for the treatment of heart failure with preserved ejection fraction

Tripeptide: Chui gm 3 amino acid (VD: GHK trong GHK-Cu)

The first mechanism is the chain-breaking reaction wherein the primary antioxidant gives an electron to the existing free radical

Recent CV outcome trials (CVOTs) have identified newer therapeutic agents with CV benefits, such as sodium-glucose cotransporter-2 (SGLT-2) inhibitors reducing hospitalization for HF and glucagon-like peptide-1 (GLP-1) receptor agonists reducing major adverse CV events (MACE), albeit with inconsistent effects on HF outcomes (70)