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Glutamate regulates Treg cell subset differentiation and their suppressive function

Semin Cancer Biol 76:8698

At present, the FDA has approved a variety of monoclonal antibodies targeting angiogenesis signaling pathways (such as bevacizumab and cetuximab, etc.) and tyrosine kinase inhibitors (sorafenib and lenvatinib, etc.) for the treatment of tumors, and many preclinical studies have demonstrated their significant anti-tumorigenesis effects (223)