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Ginkgolide B protects against cognitive impairment in senescence-accelerated P8 mice by mitigating oxidative stress, inflammation and ferroptosis

The insulin signaling network in metabolically compromised adipocytes manifests multiple molecular defects: impaired IR activation kinetics, substantial reduction in IRS-1 tyrosine phosphorylation, marked suppression of PI3K/Akt pathway signal propagation, and pathological elevation of inhibitory serine phosphorylation events on IRS-1 (66)

This cycle is crucial for DNA synthesis and repair

An implication of the mitochondrial carrier SLC25A3 as an oxidative stress modulator in NAFLD