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Lancet Oncol 18(4):e206-e217, 2017

Its large molecular size and unstable nature mean NAD+ breaks down easily in the digestive system, making it unsuitable as an oral supplement [9]

Science 359:eaao6326 Hu Y, He W, Huang Y, Xiang H, Guo J, Che Y, Cheng X, Hu F, Hu M, Ma T, Yu J, Tian H, Tian S, Ji YX, Zhang P, She ZG, Zhang XJ, Huang Z, Yang J, Li H (2021) Fatty acid synthase-suppressor screening identifies sorting nexin 8 as a therapeutic target for NAFLD