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Description

Osteoclast overactivity is a hallmark of many bone diseases, and inhibiting osteoclast differentiation through ferroptosis has emerged as a promising strategy (Zhong et al., 2023)

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Another NAM analog-based NNMT inhibitor, 6-methoxy NAM (also known as JBSNF000088), has shown promise in decreasing body weight and enhancing insulin sensitivity in mice models of obesity induced by a high-fat diet 198