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The study centered on a previously healthy 6-year-old boy who experienced darkening of his hands and feet over four months

The procedure is usually done on an outpatient basis

doi: 10.3389/fimmu.2025.1593263 Received 13 March 2025 Accepted 26 June 2025 Published 21 July 2025 Volume 16 - 2025 Edited by Rajko Reljic, University of London, United Kingdom Reviewed by Angelo Izzo, Royal Prince Alfred Hospital, Australia Angel Alejandro Oate, University of Concepcion, Chile Premanshu Dandapat, Indian Council of Agricultural Research (ICAR), India Updates Copyright 2025 Almujri, Stylianou, Nicastri, Satti, Korompis, Li, De Voss, Polo Peralta Alvarez, Tanner, Bettencourt, Ternette and McShane