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Gorski et al

All measures were collected on the third day of each challenge week

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The interaction between CXCL12, a chemokine secreted by CAFs and epithelial BC cells, and its receptor CXCR4 on MDA-MB-231 breast cancer cells promotes the penetration by MDA-MB-231 cells of a monolayer of human brain microvascular endothelial cells (HBMECs), as well as increasing the permeability of these cells