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Description

In contrast to their protein-bound counterpart, FAAs can interact with specific receptors present on a wide variety of cells in various parts of the body, including the intestines, where they can activate specific intracellular pathways and confer physiological effects (48)

In the alternate pathway, activity of the C27 hydroxylase is preceded by that of 12 hydroxylase (CYP8B1), which adds a third hydroxyl group to the steroid nucleus, ultimately yielding the tri-hydroxy bile acid, cholic acid