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151 Although these studies demonstrated a beneficial effect of the KD on PCOS, they have limitations such as small sample size, broad age range, single-arm design, and a short intervention time interval

A 2024 study in the British Journal of Dermatology demonstrated that skin barrier dysfunction activates the NLRC4 inflammasome, creating a vicious cycle of inflammation that makes the skin highly reactive, sensitive, and prone to chronic rashes or severe acne breakouts

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