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Cryo-EM data for nanodisc samples were collected on a 300 kV Titan Krios G4 transmission electron microscope equipped with a cold field emission gun (CFEG) and a Falcon 4i direct electron detector (Thermo Fisher Scientific)

9 , 10 This may help explain why cortical cataracts are more common in African-Americans compared with Caucasians who are exposed to the same risk factors

Transcriptomics and biochemical evidence of trigonelline ameliorating learning and memory decline in the senescence-accelerated mouse prone 8 (SAMP8) model by suppressing proinflammatory cytokines and elevating neurotransmitter release