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Nitrous oxide, also called "laughing gas" or "hippie crack," is used as a painkiller during labor and for whipping cream in catering

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Mechanistically, USP7-mediated deubiquitination of H2BK120ub facilitates PRMT6-dependent deposition of the repressive mark H3R2me2a, concomitant with the exclusion of activating H3K4me3