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Moreover, gliomas exhibit a high dependency on glutamine uptake, whose catabolite glutamate subsequently reduces their vulnerability to ferroptosis by exchanging with extracellular cystine[186]

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Extracts taken from neurons experiencing strong synaptic activity in the previous 24 h exhibited substantially more GCL activity than did extracts from control neurons (Fig

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Favia et al., Pharmacological targets of metabolism in disease: opportunities from macrophages

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