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A narrative review concluded that the practice is controversial because there are no standardized dosing protocols and nearly onethird of patients report adverse effects, ranging from mild gastrointestinal symptoms to liver dysfunction and lifethreatening allergic reactions

The peptide appears to act through direct interaction with adipocytes (fat cells), potentially involving activation of hormone-sensitive lipase (HSL) and modulation of -adrenergic receptor signaling pathways

The above evidence suggests that prevention of excessive growth of VSMCs may be one underlying mechanism by which garlic and its constituents ameliorate elevated blood pressure

Most (8085%) of the cellular GSH are in the cytosol, 1015% is in the mitochondria and a small percentage is in the endoplasmic reticulum [68]