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The aging process in different individuals may be driven by range of factors, including genomic instability, telomere attrition, epigenetic alterations, proteostasis loss, mitochondrial dysfunction, dysregulated nutrient-sensing pathways, cellular senescence, stem-cell exhaustion, and abnormal intercellular communication (Figure 1

7,13,132,133 A thorough understanding of the key factors that maintain the stability of TI-Tregs may provide new opportunities for improving antitumor immunotherapy

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References "Sustainability of Preventative Botox for the Anti-Aging Process," International Journal of Medical Science and Research , November 23, 2023.