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From systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) to MS and autoimmune skin disorders, the disruption of proteostasis not only amplifies disease pathology but also renders conventional therapies less effective

Trk H-P, Glas J, Tonenchi L, Mussack T, Folwaczny C (2004) Polymorphisms of the lipopolysaccharide-signaling complex in inflammatory bowel disease: association of a mutation in the Toll-like receptor 4 gene with ulcerative colitis

Extensive research has been dedicated to evaluating the role of ITCs and GLSs in the chemoprevention of cancers [5]

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