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H 2 S was also found to impact cellular signaling pathways, such as phosphoinositide 3-kinase (PI3K)/protein kinase B (Akt), mitogen-activated protein kinase (MAPK), and Janus kinase (JAK)/signal transducer and activator of transcription (STAT) (Tao et al., 2024)

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In a report on comorbidities among COVID-19 patients in Wuhan, the original epicenter of what became the COVID-19 pandemic, the odds ratio for severe illness was 3.47 (95% CI: 1.0211.75, n = 222) for patients with anemia ( n = 1099), Hb levels were significantly lower in patients with severe illness than in those with non-severe COVID-19 disease