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Excessive glucocorticoid production and/or elevated basal glucocorticoids, as can occur with chronic stress and mood disorders ( EARLY LIFE HPA AXIS DEVELOPMENT AND ITS EFFECTS ON EATING BEHAVIOR Lifetime experience, whether acute or chronic, clearly shapes both HPA axis and eating behavior

Krzystyniak, A [29] and Qu, Y [19] respectively conducted studies on depression using chronic unpredictable stress (CUS) and knockout of Nrf2 as models

Irritable Bowel Syndrome Functional gastrointestinal disorders (FGID) are multifactorial diseases with poorly characterized pathophysiology

Mol Biol Cell 26:29572962 Kollman JM, Merdes A, Mourey L, Agard DA (2011) Microtubule nucleation by gamma-tubulin complexes